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Center for Bionanoscience Research (CIBION), National Scientific and Technical Research Council (CONICET) Physics Department, Faculty of Exact and Natural Sciences, University of Buenos Aires (UBA)

Using optical methods, we explore the properties and technological applications of nanoparticles, single molecules, nanostructured materials, supramolecular assemblies, biological and hybrid nanosystems.

The Applied nanoPhysics Group was launched in October 2009 at the Physics Department, Faculty of Exact and Natural Sciences, of the University of Buenos Aires (UBA)

In 2012 we moved our labs to the Center for Bionanoscience Research (CIBION) of the National Scientific and Technical Research Council (CONICET), while Prof. Stefani still holds his position at the Physics Department of the University of Buenos Aires.

CURRENT RESEARCH ACTIVITIES

Fluorescence nanoscopy.

Super-resolution fluorescence microscopy, also known as fluorescence nanoscopy, has revolutionized biological imaging because they provide deep sub-wavelenght spatial resolution while keeping the low-invasiveness of far-field optical interrogation. We apply and optimize well-established methods like STED and STORM, and develop new ones, such as MINFLUX, and open-source software for fluorescence nanoscopy. With them, we address questions of cellular and neuronal biology.

Optical printing colloidal nanoparticles.

Colloidal chemistry enables the fabrication of nanoparticles of different shapes, sizes and material compositions, that exhibit unique physical and chemical properties, inexistent in bulk materials. In order to make use of those properties in devices and circuits, it is necessary to develope methods to bring the colloidal nanoparticles from the liquid phase to specific locations of solid substrates. We address this challenge using optical forces.

Self-assembled Nanophotonic Devices.

Semiconductor-based devices are approaching intrinsic limits of speed and heat dissipation. Optical devices are faster and practically loss-less, but their size miniaturization is limited by the wavelength of light. Nanophotonics and Plasmonics deals with the manipulation of light at the nanoscale. We investigate light-matter interaction between single-photon emitters and metallic nanoparticles organized in nanodevices by self-assembly.

LATESTS NEWS

Estimating how hot is an illuminated nanoparticle

In our recent paper in ACS Nano by Mariano Barella et al., we present a nanothermometry technique based on anti-Stokes photoluminescence (PL) emission. Acquiring a hyperspectral confocal image we can obtain the photothermal coefficient of single nanoparticles (NPs) and estimate their temperature increase when they are being irradiated. Plasmonic NPs [...]

Buscamos candidatos para becas CONICET

Si estás buscando hacer un doctorado o un postdoctorado, fijate las oportunidades que tenemos en nuestro grupo. Contactanos que la convocatoria a becas CONICET ya está abierta!

Welcome Romina, Gonzalo, Florencia and Fernando!

New members joined the group. Unfortunately, they start activities in the middle of COVID-19 isolation. We work from home while we look forward to going back to the lab... Welcome Romina, Gonzalo, Florencia and Fernando! Dr. Romina Landa and Ph.D. candidate Gonzalo Escalante will be working [...]

Detecting molecular organization in sparse single molecule localization images

In our recent work by Alan Szalai et al, we present a method to detect underlying molecular organization invisible to the eye in low-density single-molecule localization microscopy (SMLM) images. SMLM is fantastic to obtain super-resolved fluorescence images. However, it is often the case that the density of localizations is [...]

New equipment for the lab!

We received a shipment with various instruments and equipment coming from Göttingen, as a generous donation of the Max-Planck Society organized by Dr. Thomas Jovin. All the team was very happy and helped with the unloading and unpacking... Thank you, Tom, [...]

Revealling the NEDDylome

We contributed with super-resolution fluorescence imaging to this wonderful work led by our collaborator Dr. Damián Refojo (IBIOBA-CONICET, Max-Partner Institute), and his colleagues from Genentech Dr. Donald S. Kirkpatrick and Dr. Morgan Sheng Neddylation is the post-translational protein modification most closely related to ubiquitination. Whereas the ubiquitin-like protein [...]

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GROUP MEMBERS

PROF. DR. FERNANDO D. STEFANI
PROF. DR. FERNANDO D. STEFANIPrincipal Investigator
DR. LUCÍA LÓPEZ
DR. LUCÍA LÓPEZLab Manager
DR. IANINA L. VIOLI
DR. IANINA L. VIOLIAssistant Researcher (INS-UNSAM, CIBION)
Synthesis, modification and optical manipulation of colloidal nanoprticles
DR. JULIÁN GARGIULO
DR. JULIÁN GARGIULOAssistant Researcher (INS-UNSAM, CIBION)
Optical printing colloidal nanoparticles. Plasmon-assisted chemistry.
DR. MARIANO BARELLA
DR. MARIANO BARELLAPostdoc
Nanoscale thermophoresis and thermo-osmosis
DR. ALAN SZALAI
DR. ALAN SZALAIPostdoc
Visualization of neuronal structures with fluorescence nanoscopy
LUCIANO MASULLO
LUCIANO MASULLOPhD candidate in Physics (University of Buenos Aires)
Fluorescence nanoscopy. MINFLUX.
CECILIA ZAZA
CECILIA ZAZAPhD candidate in Physics (University of Buenos Aires)
Optical printing colloidal nanoparticles and DNA origami structures
LUCIANA MARTÍNEZ
LUCIANA MARTÍNEZPhD candidate in Physics (University of Buenos Aires)
Plasmon-assisted chemistry
SANTIAGO SOSA
SANTIAGO SOSAPhD candidate in Biological Chemistry (University of Buenos Aires)
Nanofabrication by protein self-assembly
LARS RICHTER
LARS RICHTERMaster candidate in Physics (Humboldt University of Berlin)
MINFLUX nanoscopy
DR. ROMINA LANDA
DR. ROMINA LANDAPostdoc
Super-resolution fluorescence microscopy of chromatin
GONZALO ESCALANTEPhD candidate in Chemistry (University of Buenos Aires)
Super-resolution imaging of chromatin
FLORENCIA EDORNA
FLORENCIA EDORNAUndergraduate in Physics (University of Buenos Aires)
Spatially modulated foci for super-resolution microscopy
FERNANDO CAPRILESUndergraduate in Physics (University of Buenos Aires)
MINFLUX nanoscopy
GROUP PICTURES

ALUMNI

Dr. Jesica Pellegrotti – National University of Comahue – Neuquén, Argentina
Dr. Yanina Álvarez – Postdoc at National University of Singapore  – Singapore
Dr. Eduardo Perassi – Assistant Professor at National University of Córdoba – Córdoba, Argentina
Dr. Emiliano Cortés – Professor at the Nano Institute Munich, Ludwig-Maximilians-University Munich, Germany
Dr. Martín Diego Bordenave – Satellite Optical Integration Engineering at Satellogic – Buenos Aires, Argentina
Dr. Julián Gargiulo – Researcher at National University of San Martin – Buenos Aires, Argentina
Dr. Federico Barabas – Associate Data Scientist at Spotify – Stockholm, Sweden
Dr. Rodrigo Ponzio – Postdoc at National University of Río Cuarto – Córdoba, Argentina

 

Fernando Díaz
Andrés Benassi – Geophysicist at Total – Houston, Texas, USA
Alfredo Sánchez – Graduate Student at Instituto Balseiro – Bariloche, Argentina
Santiago Cerrotta – Graduate Student at National Technological University – Campana, Buenos Aires, Argentina
Bruno Scocozza – Graduate Student at Max-Planck-Institute of Molecular Physiology – Dortmund, Germany
Germán Chiarelli – Graduate Student at University of Fribourg – Fribourg, Switzerland
Robin Puchert – Graduate Student at University of Regensburg – Regensburg, Switzerland
Dr. Ianina Violi – Researcher at National University of San Martin – Buenos Aires, Argentina
Dr. Bruno Siarry

COLLABORATORS

STEFAN HELL Max-Planck-Institute for Biophysical Chemistry (Göttingen, Germany)

PHILIP TINNEFELD Ludwig-Maximilians-University Munich (Germany)

ALFREDO CÁCERES Instituto de Investigación Médica Mercedes y Martín Ferreyra (Córdoba, Argentina)

STEFAN MAIER Ludwig-Maximilians-University Munich (Germany)

THOMAS JOVIN Max-Planck-Institute for Biophysical Chemistry (Göttingen, Germany)

ANDREA BRAGAS University of Buenos Aires (Argentina)

JOCHEN FELDMANN Ludwig-Maximilians-University Munich (Germany)

NIEK VAN HULST Institute of Photonic Sciences (Barcelona, Spain)

EDUARDO CORONADO Universidad Nacional de Córdoba (Córdoba, Argentina)

PAVEL ZEMANEK Czech Academy of Sciences (Brno, Czech Republic)

DAMIAN REFOJO Biomedicine Research Institute of Buenos Aires (Argentina)

RODRIGO PALACIOS Universidad Nacional de Río Cuarto (Córdoba, Argentina)

OSCAR CAMPETELLA Universidad Nacional de General San Martín (Buenos Aires, Argentina)

OMAR AZZARONI Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas (La Plata, Buenos Aires, Argentina)

GUILLERMO ACUNA University of Fribourg (Switzerland)

GALO SOLER ILLIA Universidad Nacional de General San Martín (Buenos Aires, Argentina)

SPONSORS

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